C-D Principal Investigators

Explore Principal Investigators in our institute with surnames beginning C-D.

miRNA mimics preserve the native microvasculature network following ischaemic injury

Reader

We study how impaired endothelial cells can lead to vascular diseases, and we work to develop treatments to restore their healthy function.

A.Caporali@ed.ac.uk 

Using machine learning to analyse MRI scans, we have measured bone marrow fat in >50,000 people, thereby revealing how it impacts human health

Reader

I study how diet & body fat, especially bone marrow fat, affect our health, and how this differs between the sexes. I promote open, dependable science.

W.Cawthorn@ed.ac.uk

INCR logo on blue background

MacDonald Chair of Neurology

The Chandran group links clinical activity with laboratory research into two neurodegenerative diseases: multiple sclerosis and motor neurone disease.

Siddharthan.Chandran@ed.ac.uk

Ultra-high-resolution photon-counting CT imaging of a coronary artery in a patient with coronary artery disease and a previous stent.

Senior Research Fellow

I research heart attacks using routine data and advanced imaging techniques to improve diagnosis and treatment for patients.

A.R.Chapman@ed.ac.uk

Dr Fiona A Chapman

INCR logo on blue background

Senior Clinical Research Fellow

My research focuses on understanding, detecting and treating heart disease and kidney disease in women.

Fiona.Chapman@ed.ac.uk

Distribution of developmental and psychiatric disorders by age in children with epilepsy

Personal Chair Paediatric Neurology & Clinical Epidemiology

We aim to identify causes of epilepsies, understand additional problems beyond seizures, and develop earlier diagnostics and improved treatments.

R.Chin@ed.ac.uk

Image credit: Pediatrics,2016;138(3). doi:10.1542/peds.2016-0921

Neurobiology of natural behaviour

Simons ESAT Fellow

We study how the brain and body integrate social and environmental information to shape natural behaviour across species and the lifespan.

Ann.Clemens@ed.ac.uk

INCR logo on blue background

Personal Chair of Translational Neuroscience

Our lab uses a range of technologies to develop novel treatments for neurodevelopmental disorders based on deep understanding of molecular pathology.

Stuart.Cobb@ed.ac.uk

Spatial transcriptomics highlights influx of immune cells (orange) and scar-producing fibroblasts (yellow) in the injured kidney.

Senior Clinical Lecturer

Our group analyses genes/proteins switched on/off in diseased kidneys to develop new therapies to prevent disease progression or enable kidney repair.

Bryan.Conway@ed.ac.uk

The false colour image reveals a presynapse after activity, with neurotransmitter-containing SVs (pink) and endosomes formed by endocytosis (blue).

Personal Chair of Neuronal Cell Biology

We investigate how brain cells sustain their communication to maintain brain health and how dysfunctional communication culminates in human disease.

M.Cousin@ed.ac.uk

INCR logo on blue background

Clinical Research Fellow

I study heart disease using new imaging modalities, investigating why it develops and identifying potential biomarkers or targets for treatment.

Neil.Craig@ed.ac.uk

Brain cell diversity: neurons (blue), synapses (red), oligodendroglia (green, yellow, orange), microglia (white), astroglia (magenta).

Personal Chair of Glial Cell Biology

About half of our brain cells are not neurons. We study what these cells do and why they matter.

Tim.Czopka@ed.ac.uk

synbiopattern: en synthetic biological system that  self-oragnizes into colour patterns

Personal Chair of Experimental Anatomy

I research the development of biological form in foetal life, and how we can use synthetic biology approaches to engineer new, designed, forms.

Jamie.Davies@ed.ac.uk

The process of taking new blood tests and drugs from the laboratory into patients

Personal Chair of Clinical Pharmacology

We do studies in patients that aim to improve the treatment of liver damage that occurs due to medications.

James.Dear@ed.ac.uk

CCR2+ monocytes are the source of scar associated macrophages in the injured kidney. White:Dapi Green:COL1a1 Red:CCR2+ TdT+ myeloid cells, Blue:IBA1.

Reader

We study how immune cells and non-coding RNAs influence injury and repair in the kidney and cardiovascular system.

Laura.Denby@ed.ac.uk

Renal function in Drosophila is executed by the coordinated physiological activities of stellate cells (green) & surrounding principal cells (red).

Personal Chair of Developmental Biology and Physiology

We study organ form & function to discover how cells self-organise into complex anatomies & work for the benefit of the organism.

Barry.Denholm@ed.ac.uk

INCR logo on blue background

Personal Chair in Stroke Medicine // Personal Chair of Stroke Medicine

I am a consultant stroke physician and also run a programme of research aiming to help detect, prevent and treat the complications of stroke.

Martin.Dennis@ed.ac.uk

Dr Martin Denvir

INCR logo on blue background

Reader in Cardiology

My research spans laboratory to bedside addressing heart development & immune cell responses in zebrafish to clinical heart failure and palliative care.

Martin.Denvir@ed.ac.uk

INCR logo on blue background

Clinical Research Fellow // Professor of Nephrology

We focus on cardiovascular risk associated with chronic kidney disease from early in the disease trajectory through to end-stage renal failure.

Bean.Dhaun@ed.ac.uk

The eye is a biological barometer of neurovascular health and a window to the brain.

NES Personal Chair of Clinical Ophthalmology

The aging eye and brain are vulnerable to neurodegeneration causing sight loss and dementia; we study prediction and prevention.

Baljean.Dhillon@ed.ac.uk

Two astrocytes in green enwrapping brain blood vessels in magenta.

UK DRI Programme Leader (Fellow)

We investigate the contribution to brain function and dementia made by communication of brain support cells called astrocytes with the vasculature.

B.Diaz-Castro@ed.ac.uk

Image credit: Carlos Parra-Pérez

INCR logo on blue background

Senior Lecturer

We investigate how gut microbiota and their metabolites influence α-synuclein aggregation in Parkinson’s disease, with a focus on clinical translation.

Maria.Doitsidou@ed.ac.uk

Rat hippocampal neuron at 14 days in vitro (DIV): Camk2a mRNA (orange), MAP2 (cyan).

Simons ESAT Fellow

Our lab explores how neurons move and use RNA to make proteins at synapses, helping the brain learn, adapt, and store memories.

Pdonlin@exseed.ed.ac.uk

CoDE-ACS and CoDE-HF decision-support tools displayed in an Emergency Department setting to support rapid diagnosis of serious heart conditions.

Senior Data Scientist in Cardiovascular Health Data Science

I develop AI decision-support tools to help doctors diagnose serious heart conditions quickly and accurately in the Emergency Department.

Dimitrios.Doudesis@ed.ac.uk

Image credit: AI generated image

Projection neurons in layer 5 of primary motor cortex that drive execution of simple and complex movements.

Personal Chair of Cellular and Systems Neuroscience

Our research focusses on understanding how the nervous system selects, plans and executes flexible movements.

Ian.Duguid@ed.ac.uk

INCR logo on blue background

Senior Lecturer

My work aims to determine whether loss of normal tau function contributes to synaptic pathology in Alzheimer’s disease and related disorders.

Claire.Durrant@ed.ac.uk

INCR logo on blue background

Personal Chair of Clinical Cardiology

I apply multi-modality imaging techniques (echocardiography, CT, MRI, PET) to the study of cardiovascular disease and improve patient care.

Marc.Dweck@ed.ac.uk