S-T Principal Investigator

Explore Principal Investigators in our institute with surnames beginning S-T.

Rustam Al-Shahi Salman leads this research group

Personal Chair of Clinical Neurology

My clinical work and research focus on stroke. I investigate the causes of bleeding in the brain and do clinical trials of treatments to improve outcomes.

Rustam.Al-Shahi@ed.ac.uk

Starting with people with rare type of insulin resistance, we study genes, cells and animal models to work out disease mechanism.

Chair of Translational Molecular Medicine

I study rare human disorders of insulin action, both to improve their diagnosis and care, and to learn about mechanisms of related common diseases.

Rsemple@exseed.ed.ac.uk

Edinburgh Imaging - brain scan

Personal Chair of Medical Imaging and Physics

As Scientific Director of Edinburgh Imaging, I manage the scientific program and development of clinical imaging using MRI, PET and CT scanners.

Scott.Semple@ed.ac.uk

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Personal Chair of Meta Science and Translational Medicine

Our focus is on improving how biomedical studies are designed, reported and evaluated so they are more reliable and translate to better health.

Emily.Sena@ed.ac.uk

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Chair of Physiology

We invetestigate how cellular excitability is dynamically controlled, and how this regulation is disrupted in stress-related diseases.

Mike.Shipston@ed.ac.uk

Microglia (green) interacting with brain tumour initiating cells (white).

Senior Lecturer

We study how brain tumour cells hijack immune cells to support their growth and how we can block these harmful interactions to improve treatments.

Dirk.Sieger@ed.ac.uk

Inter-organelle junctions (green) between mitochondria (red) and the ER (blue) revealed by VAPB molecular complementation.  VAPB is disrupted in ALS8.

Reader

Our work uses experimental models based on inherited forms of neurodegeneration to better understand and ultimately treat these diseases.

Paul.Skehel@ed.ac.uk

Cultured striatal neurons stained for DARPP32 in red (medium spiny neuron marker) and synaptotagmin in green (pan neuronal marker).

Senior Lecturer

My research focuses on investigating the molecular mechanisms of neurodegeneration at the presynapse using Huntington’s Disease as a model.

K.Smillie@ed.ac.uk

A collection of abnormal protein in the brain of a patient with variant CJD.

Personal Chair Neuropathology

I use human brain tissues, generously donated by patients when they die, to study common human disorders such as dementia and stroke.

Col.Smith@ed.ac.uk

Representation of 24-hour radar sleep data collection in a person with bipolar disorder.

Chair of Psychiatry

My work investigates the causes and treatment of bipolar disorder, combining circadian neuroscience, metabolic and data science approaches.

D.Smith@ed.ac.uk

High-resolution image of synapses (green and grey), cells (blue) and a tau pathology (red) in Alzheimer's disease brain tissue.

Personal Chair of Neurodegeneration

Our research focuses on the brain changes that cause Alzheimer’s disease, related dementias, and age-related cognitive decline.

Tara.Spires-Jones@ed.ac.uk

Patrick Wild Centre

Senior Clinical Research Fellow

As a medical academic psychiatrist, I research better ways to understand and support people with genetic conditions affecting brain development.

Andrew.Stanfield@ed.ac.uk

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Rowling Scholar // Senior Clinical Research Fellow

Mstavrou@ed.ac.uk

A) PET/MRI and B) thermal images to quantify brown adipose tissue activity during mild cold exposure, and the effect of the SSRI sertraline.

Personal Chair of Endocrinology

Our group investigates how to increase energy expenditure as a novel treatment for obesity and associated diseases such as diabetes and heart disease.

Roland.Stimson@ed.ac.uk

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Senior Clinical Lecturer in Neonatal Neuroscience

We use stem cell models and neonatal brain MRI to study sex differences in how the brain responds to infection in early life.

Gsulliv2@ed.ac.uk

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Senior Lecturer

Our research is focused on how neural circuits for cognition are built and operate.

Gsurmeli@exseed.ed.ac.uk

First healthy human whole-body images of [18F]LW223, a new imaging marker of inflammation. Data published in the EJNMMI.

Personal Chair of Translational Molecular Imaging

My research is focused on developing new medical imaging tools, including whole-body methods of analysis, to help diagnosis and treatment of patients.

Adriana.Tavares@ed.ac.uk

Human Stem cell derived neuromuscular organoids.

Senior Research Fellow

I aim to understand cellular and molecular mechanisms leading to neurodegeneration in ALS/FTD and develop novel therapeutics.

Bthangar@exseed.ed.ac.uk

Immunostaining of a cortical organoid revealing primary cilia protruding from the surface of neural stem cells.

Reader

We are working out how primary cilia control cell signalling in the developing brain and how this regulation goes wrong in autism spectrum disorders.

Thomas.Theil@ed.ac.uk

Examples of human brain MRI measurements applied to sheep models of health and disease, including the grey mater (thinking) and white matter (wiring).

Senior Clinical Lecturer in Radiology

I use brain imaging to improve diagnosis and treatment of conditions including dementia, tumours, inflammation, head injury and mental health.

Gerard.Thompson@ed.ac.uk

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Personal Chair of Forensic Psychiatry

L.D.G.Thomson@ed.ac.uk

3D-printed MRI phantom generating realistic tissue and vascular dynamic signals following injection of contrast agent.

Senior Research Fellow

I develop and evaluate quantitative medical imaging methods, and use these to investigate mechanisms and treatments of neurological diseases.

M.J.Thrippleton@ed.ac.uk

Image credit: From https://doi.org/10.1002/mrm.30595

Our approaches: combining behavioural paradigms with brain imaging and cardiovascular monitoring.

Senior Lecturer

We study how biological factors shape brain networks, social and emotional processing, and autonomic and cardiovascular function across development.

S.Till@ed.ac.uk

‘Sensing touch’: A tactile (Meissner) corpuscle - a sensory end organ exquisitely sensitive to fine touch.

Reader

We investigate processing of touch and pain by the nervous system and how this is dysregulated in neurodevelopmental disorders and pain conditions.

Carole.Torsney@ed.ac.uk