CANCELLED - Due to the very heavy snowfalls and subsequent travel difficulties, this lecture has regretfully been cancelled Wednesday 8th December 2010 This Scottish Society for Experimental Medicine meeting is being held on Wednesday 8th December from 09.45 at the Queens Medical Research Institute, Little France. The keynote speaker will be Professor Siddharthan Chandran, MacDonald Professor of Neurology, who will talk on "Neurodegeneration and the promise of brain repair" Programme 09:45 - 10:15 Coffee & Registration Session 1 10:15 - 10:30 Hyperinsulinemia in Fat-specific Androgen Receptor Knockout Mice is Associated with Elavated Retinol-Binding Protein-4 Levels. * McInnes KJ, Hunger NI, Smith LB, Saunders PTK, Andrew R, Walker BR 10:30 - 10:45 Neuronal immunoreactivity to beta-amyloid precursor protein in the hippocampus and temporal lobe following traumatic brain injury * Smith DW, Johnson VE, Stewart JE, Smith DH, Stewart 10:45 - 11:00 Endothelin-1 stimualtes human podocyte Endothelilin-1 & pro-inflammatory cytokine production & induces structural alterations * Owen EL, Dhaun N, Mathieson PW, Saleem M, Webb DJ, Kluth DC 11:00 - 11:15 Macrophage therapy for experimental liver fibrosis recruits host effector cells improving fibrosis, regeneration and function * Thomas JA, Pope C, Wojtacha, Gordon-Walker T, Robson A, Hartland S, Ramachandran P, Hume D, Iredale JP, Forbes SJ 11:15 - 11:30 Enhanced resolution of established neutrophilic inflammation in the lung by a novel cyclin-dependent kinase inhibitor * Lucas CD, Duffin R, Hasslett C, Rossi AG Keynote Lecture 11:30 - 12:15 Neurodegeneration and the promise of brain repair Siddharthan Chandran, MacDonald Professor of Neurology 12:15 - 13:45 Lunch & Posters Session 2 13:45 - 14:00 Health Behaviours in Severely Obese Women Prior to Conception and During Pregnancy * Duthie L, Mohd-Shukri N, Forbes S, Dension FC, Norman JE, Reynolds RM 14:00 - 14:15 High prevalence of sleep disordered breathing among pregnancies associated with obesity * Haywood MJ, Rich SH, Rhia RL, Hill EA, Forbes S, Dension FC, Norman JE, Reynolds RM 14:15 - 14:30 The effect of omacetaxine with imatinib in Chronic Myeloid Leukaemia * Melchzidek K, Allan E, Holyoake T, Jørgensen H 14:30 - 14:45 Left Ventricular Strain Measured by Displacement Encoded Magnetic Resonance Imaging: Initial Validation Against the Transmural Extent of Infarct Scar * Smith C, McComb C, Payne A, Foster J, Steedman T, Barrett R, Gao H, Woodward R, Gilchrist J, Saul A, Clark C, Oldroyd KG, Tzemos N, Berry C 14:45 - 15:15 Coffee & Business Meeting Members of the SSEM to attend Business Meeting Session 4 15:15 - 15:30 The use of B-type natriuretic peptide (BNP) to identify silent pancardiac target organ damage in patients requiring primary prevention * Nadir MA, Rekhraj S, Lim TK, Wei L, Davidson J, Lang CC, MacDonald TM, Struthers AD 15:30 - 15:45 The splice of life: an attempt to create a red fluorescent reporter of Hsd1b2 gene expression illustrating the pitfalls of a BAC transgenic approach * Hunter RW, Mullins LJ, Sharp M, Bailey MA, Mullins JJ 15:45 - 16:00 Anti-inflammatory properties of 5α-Reduced Glucocorticoids: Potential Dissociated Steroids * Nixon M, Duffin R, Rossi AG, Walker BR, Andrew R 16:00 Presentation of Prizes & Close of Meeting Publication date 18 Jun, 2015